Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
xerDTyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (324 aa)    
Predicted Functional Partners:
Tpau_2376
PFAM: NUDIX hydrolase; KEGG: mjl:Mjls_2958 NUDIX hydrolase.
  
  
 0.920
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.872
Tpau_2374
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: rer:RER_32590 Soj/ParA-related protein.
 
   
 0.765
Tpau_1771
PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; KEGG: rha:RHA1_ro06750 DNA translocase FtsK.
 
   
 0.754
Tpau_2379
KEGG: rha:RHA1_ro00933 hypothetical protein.
 
    0.737
Tpau_2378
KEGG: rer:RER_32630 channel protein.
  
    0.711
Tpau_2372
Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
     
 0.643
Tpau_2373
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
     
 0.641
cmk
KEGG: nfa:nfa20120 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
     
 0.595
der
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
     
 0.579
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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