Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (295 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.967
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.949
Tpau_2383
TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: nfa:nfa19960 putative cytotoxin/hemolysin; SMART: RNA-binding S4 domain protein.
  
  
 0.947
Tpau_0191
KEGG: mva:Mvan_0120 NAD(P) transhydrogenase subunit alpha; TIGRFAM: NAD(P) transhydrogenase, alpha subunit; PFAM: alanine dehydrogenase/PNT domain protein.
     
 0.925
Tpau_2386
KEGG: rer:RER_32690 hypothetical protein.
 
   
 0.915
cobB
PFAM: Silent information regulator protein Sir2; KEGG: mbt:JTY_1185 NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.910
Tpau_2381
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
   
 0.908
Tpau_0192
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.906
Tpau_3050
PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; KEGG: nfa:nfa45350 NADH pyrophosphatase.
     
 0.903
Tpau_3190
PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: msm:MSMEG_5422 nucleoside triphosphate pyrophosphohydrolase.
     
  0.900
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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