Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_2385KEGG: rop:ROP_06710 putative hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase. (316 aa)    
Predicted Functional Partners:
Tpau_2386
KEGG: rer:RER_32690 hypothetical protein.
  
 
 0.989
Tpau_0498
PFAM: iron-containing alcohol dehydrogenase; 3- dehydroquinate synthase; KEGG: tfu:Tfu_2801 glycerol dehydrogenase.
  
 
 0.932
Tpau_1005
PFAM: Carbohydrate kinase, FGGY-like; KEGG: rop:ROP_63250 glycerol kinase.
  
 
 0.907
Tpau_2018
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: mmi:MMAR_1649 NADP-dependent alcohol dehydrogenase Adh.
     
  0.900
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.895
Tpau_2381
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
     
 0.881
Tpau_2383
TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: nfa:nfa19960 putative cytotoxin/hemolysin; SMART: RNA-binding S4 domain protein.
     
 0.843
Tpau_2384
Hypothetical protein.
       0.771
cmk
KEGG: nfa:nfa20120 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
  
    0.494
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
 
    0.475
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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