Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_2639PFAM: protein of unknown function YGGT; KEGG: rop:ROP_08090 hypothetical membrane protein. (99 aa)    
Predicted Functional Partners:
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
 
  
 0.971
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.815
Tpau_2638
KEGG: mkm:Mkms_3310 DivIVA family protein; TIGRFAM: DivIVA domain; PFAM: DivIVA family protein.
 
  
 0.778
Tpau_2801
PFAM: DNA polymerase III delta; KEGG: nfa:nfa13940 hypothetical protein.
 
   
 0.773
Tpau_2641
Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.764
rbpA
Conserved hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
     0.756
Tpau_1882
KEGG: mab:MAB_3005c hypothetical protein.
  
     0.741
Tpau_3577
KEGG: rop:ROP_49220 hypothetical protein.
  
     0.726
Tpau_2642
PFAM: protein of unknown function DUF152; KEGG: rha:RHA1_ro01084 hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
  
  
 0.725
Tpau_3040
KEGG: rer:RER_22280 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: Protein of unknown function DUF2342.
  
     0.687
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: low (32%) [HD]