Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_2672TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: mgi:Mflv_2971 phospho-2-dehydro-3- deoxyheptonate aldolase; PFAM: DAHP synthetase class II; Belongs to the class-II DAHP synthase family. (467 aa)    
Predicted Functional Partners:
Tpau_3331
Chorismate mutase; KEGG: nfa:nfa49960 hypothetical protein; TIGRFAM: chorismate mutase; PFAM: Chorismate mutase.
   
 
 0.963
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
    
 0.950
Tpau_3141
Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
     
 0.911
Tpau_3314
KEGG: mkm:Mkms_2781 chorismate mutase; TIGRFAM: chorismate mutase; PFAM: Chorismate mutase.
   
 
 0.818
Tpau_2522
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
     
 0.815
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
    
 0.805
Tpau_0511
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
     
  0.800
Tpau_3949
PFAM: Transketolase domain protein; Transketolase central region; KEGG: rha:RHA1_ro00814 transketolase, C-terminal subunit.
     
  0.800
Tpau_3950
PFAM: Transketolase domain protein; KEGG: mno:Mnod_5660 transketolase domain protein.
     
  0.800
Tpau_2673
Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
     
 0.748
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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