Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa)    
Predicted Functional Partners:
Tpau_2044
TIGRFAM: anthranilate synthase component I; KEGG: mab:MAB_2647c anthranilate synthase component I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein.
 
 0.999
Tpau_0026
KEGG: rop:ROP_35100 anthranilate synthase component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I.
  
 0.998
trpC
KEGG: mab:MAB_2645c indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
  
 0.997
trpF
KEGG: rer:RER_48400 phosphoriborylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family.
 
 
 0.997
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.991
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.986
Tpau_3238
Para-aminobenzoate synthase, subunit I; KEGG: mjl:Mjls_4651 aminodeoxychorismate synthase component I; TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like.
 
 
 0.980
hisA
TIGRFAM: bifunctional HisA/TrpF protein; KEGG: rop:ROP_07500 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino) methylideneamino] imidazole-4- carboxamide isomerase; PFAM: histidine biosynthesis protein.
    
 0.943
Tpau_2691
KEGG: nfa:nfa17250 hypothetical protein.
       0.784
Tpau_2689
PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: ach:Achl_2700 YbaK/prolyl-tRNA synthetase associated region.
       0.778
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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