Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_2712PFAM: protein of unknown function DUF34; KEGG: nfa:nfa16340 hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (373 aa)    
Predicted Functional Partners:
Tpau_2711
PFAM: protein of unknown function DUF164; KEGG: nfa:nfa16390 hypothetical protein.
  
  
 0.952
Tpau_2710
PFAM: Phosphoglycerate mutase; KEGG: nfa:nfa16400 bifunctional RNase H/acid phosphatase.
  
    0.809
Tpau_2714
KEGG: mjl:Mjls_3359 putative transmembrane protein.
       0.731
hisC
KEGG: nfa:nfa18460 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.693
pat
Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.693
Tpau_2713
KEGG: rer:RER_36630 protein-tyrosine-phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight.
       0.683
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
   
 0.544
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.526
Tpau_0436
KEGG: rop:ROP_15710 putative endonuclease IV; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2.
     
 0.487
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
     0.487
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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