Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_2792KEGG: art:Arth_3745 choline/carnitine/betaine transporter; TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; Belongs to the BCCT transporter (TC 2.A.15) family. (711 aa)    
Predicted Functional Partners:
Tpau_2794
PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: aau:AAur_0512 choline oxidase.
 
  
 0.842
Tpau_2793
Betaine-aldehyde dehydrogenase; KEGG: cmi:CMM_1951 putative glycine betaine aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 0.788
Tpau_2795
KEGG: rop:ROP_09990 hypothetical protein.
       0.713
Tpau_2791
PFAM: GCN5-related N-acetyltransferase; KEGG: nca:Noca_4638 GCN5-related N- acetyltransferase.
       0.556
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
    0.529
Tpau_1334
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.459
Tpau_2968
PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; ferredoxin; molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: rha:RHA1_ro04506 xanthine dehydrogenase molybdenum binding subunit.
       0.423
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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