Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_2817PFAM: regulatory protein TetR; KEGG: rha:RHA1_ro00766 TetR family transcriptional regulator. (210 aa)    
Predicted Functional Partners:
Tpau_2816
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mav:MAV_1802 2,3-dihydroxybiphenyl-1,2- dioxygenase.
 
     0.906
Tpau_2814
PFAM: monooxygenase FAD-binding; KEGG: mmi:MMAR_2987 3-(3-hydroxyphenyl)propionate hydroxylase.
 
   
 0.822
Tpau_2815
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: mav:MAV_1803 2-hydroxyhepta-2,4-diene-1,7- dioate isomerase.
 
     0.790
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
       0.541
Tpau_2818
PFAM: Domain of unknown function DUF1994; KEGG: mkm:Mkms_1983 hypothetical protein.
       0.511
Tpau_4173
PFAM: Mammalian cell entry related domain protein; KEGG: nfa:nfa11160 putative Mce family protein.
  
     0.479
Tpau_2812
PFAM: cyclase/dehydrase; KEGG: mbt:JTY_0876 hypothetical protein.
       0.478
Tpau_1197
KEGG: nfa:nfa26160 hypothetical protein.
  
     0.443
Tpau_3868
KEGG: cgt:cgR_0900 hypothetical protein.
  
     0.441
Tpau_2805
KEGG: rha:RHA1_ro01294 hypothetical protein.
 
     0.429
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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