Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Tpau_2875KEGG: nfa:nfa42560 hypothetical protein. (398 aa)    
Predicted Functional Partners:
Tpau_2874
KEGG: rer:RER_23860 hypothetical protein.
 
     0.827
Tpau_2876
KEGG: sen:SACE_2977 BadM/Rrf2 family transcriptional regulator; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074.
       0.663
Tpau_2873
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: nfa:nfa42540 putative two-component system sensor kinase.
       0.544
Tpau_2872
KEGG: rer:RER_23880 NarL family two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; Bacterio-opsin activator HTH domain protein; sigma-70 region 4 domain protein; SMART: regulatory protein LuxR; response regulator receiver.
       0.540
Tpau_2877
Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
       0.494
Tpau_3058
PFAM: Abortive infection protein; KEGG: mab:MAB_0497 hypothetical protein.
 
     0.482
Tpau_0365
KEGG: nfa:nfa54850 hypothetical protein.
  
     0.457
pfkA
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
       0.435
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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