Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
Tpau_2884PFAM: AMP-dependent synthetase and ligase; Enoyl- CoA hydratase/isomerase; KEGG: rha:RHA1_ro05319 CoA ligase. (807 aa)    
Predicted Functional Partners:
Tpau_3480
Mycocerosate synthase., 6-deoxyerythronolide-B synthase; KEGG: sen:SACE_4141 type I modular polyketide synthase; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; KR domain protein; Acyl transferase; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding.
  
 0.984
Tpau_3476
KEGG: stp:Strop_2778 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Acyl transferase; KR domain protein; Thioesterase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding.
  
 0.978
Tpau_3477
PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: sgr:SGR_6073 putative type-I PKS.
  
 0.968
Tpau_1315
PFAM: MaoC domain protein dehydratase; Beta- ketoacyl synthase; Acyl transferase; domain of unknown function DUF1729; KEGG: nfa:nfa12570 putative fatty acid synthase.
  
 0.917
Tpau_0175
PFAM: Beta-ketoacyl synthase; Acyl transferase; Thioesterase; phosphopantetheine-binding; KEGG: rha:RHA1_ro04065 polyketide synthase.
  
 0.909
Tpau_1373
Thioester reductase domain protein; KEGG: mab:MAB_2962 fatty-acid-CoA ligase FadD; TIGRFAM: thioester reductase domain protein; PFAM: Male sterility domain; AMP-dependent synthetase and ligase; phosphopantetheine-binding.
  
 0.884
Tpau_2882
PFAM: Aldehyde Dehydrogenase; KEGG: rha:RHA1_ro05322 dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 0.880
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.864
Tpau_3478
PFAM: Acyl transferase; short-chain dehydrogenase/reductase SDR; Beta-ketoacyl synthase; KR domain protein; Erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: sen:SACE_4141 type I modular polyketide synthase.
  
 0.855
rpsB
KEGG: nfa:nfa41310 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
    
 0.850
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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