| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Tpau_2580 | Tpau_2965 | Tpau_2580 | Tpau_2965 | TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: rer:RER_30050 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | KEGG: msm:MSMEG_1293 xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. | 0.858 |
| Tpau_2580 | carB | Tpau_2580 | Tpau_2581 | TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: rer:RER_30050 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | KEGG: rha:RHA1_ro07152 carbamoyl phosphate synthase large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl- phosphate synthetase large chain domain protein; Belongs to the CarB family. | 0.996 |
| Tpau_2580 | pyrB | Tpau_2580 | Tpau_2585 | TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: rer:RER_30050 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | TIGRFAM: aspartate carbamoyltransferase; KEGG: mjl:Mjls_2404 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.983 |
| Tpau_2580 | pyrD | Tpau_2580 | Tpau_2130 | TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: rer:RER_30050 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.961 |
| Tpau_2580 | pyrE | Tpau_2580 | Tpau_0503 | TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: rer:RER_30050 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.993 |
| Tpau_2580 | pyrR | Tpau_2580 | Tpau_2586 | TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: rer:RER_30050 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.993 |
| Tpau_2961 | Tpau_2964 | Tpau_2961 | Tpau_2964 | Hydroxyisourate hydrolase; KEGG: mmi:MMAR_4947 hypothetical protein; TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | KEGG: mgi:Mflv_4787 hypothetical protein. | 0.543 |
| Tpau_2961 | Tpau_2965 | Tpau_2961 | Tpau_2965 | Hydroxyisourate hydrolase; KEGG: mmi:MMAR_4947 hypothetical protein; TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | KEGG: msm:MSMEG_1293 xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. | 0.842 |
| Tpau_2961 | Tpau_2966 | Tpau_2961 | Tpau_2966 | Hydroxyisourate hydrolase; KEGG: mmi:MMAR_4947 hypothetical protein; TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: mva:Mvan_5279 amidohydrolase. | 0.827 |
| Tpau_2961 | Tpau_2968 | Tpau_2961 | Tpau_2968 | Hydroxyisourate hydrolase; KEGG: mmi:MMAR_4947 hypothetical protein; TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; ferredoxin; molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: rha:RHA1_ro04506 xanthine dehydrogenase molybdenum binding subunit. | 0.866 |
| Tpau_2964 | Tpau_2961 | Tpau_2964 | Tpau_2961 | KEGG: mgi:Mflv_4787 hypothetical protein. | Hydroxyisourate hydrolase; KEGG: mmi:MMAR_4947 hypothetical protein; TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.543 |
| Tpau_2964 | Tpau_2965 | Tpau_2964 | Tpau_2965 | KEGG: mgi:Mflv_4787 hypothetical protein. | KEGG: msm:MSMEG_1293 xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. | 0.783 |
| Tpau_2964 | Tpau_2966 | Tpau_2964 | Tpau_2966 | KEGG: mgi:Mflv_4787 hypothetical protein. | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: mva:Mvan_5279 amidohydrolase. | 0.685 |
| Tpau_2964 | Tpau_2968 | Tpau_2964 | Tpau_2968 | KEGG: mgi:Mflv_4787 hypothetical protein. | PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; ferredoxin; molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: rha:RHA1_ro04506 xanthine dehydrogenase molybdenum binding subunit. | 0.927 |
| Tpau_2965 | Tpau_2580 | Tpau_2965 | Tpau_2580 | KEGG: msm:MSMEG_1293 xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. | TIGRFAM: orotidine 5'-phosphate decarboxylase; KEGG: rer:RER_30050 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.858 |
| Tpau_2965 | Tpau_2961 | Tpau_2965 | Tpau_2961 | KEGG: msm:MSMEG_1293 xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. | Hydroxyisourate hydrolase; KEGG: mmi:MMAR_4947 hypothetical protein; TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.842 |
| Tpau_2965 | Tpau_2964 | Tpau_2965 | Tpau_2964 | KEGG: msm:MSMEG_1293 xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. | KEGG: mgi:Mflv_4787 hypothetical protein. | 0.783 |
| Tpau_2965 | Tpau_2966 | Tpau_2965 | Tpau_2966 | KEGG: msm:MSMEG_1293 xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: mva:Mvan_5279 amidohydrolase. | 0.926 |
| Tpau_2965 | Tpau_2968 | Tpau_2965 | Tpau_2968 | KEGG: msm:MSMEG_1293 xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. | PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; ferredoxin; molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: rha:RHA1_ro04506 xanthine dehydrogenase molybdenum binding subunit. | 0.787 |
| Tpau_2965 | carB | Tpau_2965 | Tpau_2581 | KEGG: msm:MSMEG_1293 xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. | KEGG: rha:RHA1_ro07152 carbamoyl phosphate synthase large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl- phosphate synthetase large chain domain protein; Belongs to the CarB family. | 0.847 |