Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Tpau_2999KEGG: rha:RHA1_ro03276 alkyl hydroperoxide reductase subunit F; TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (525 aa)    
Predicted Functional Partners:
Tpau_3000
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
 
  
 0.993
Tpau_0449
Catalase; KEGG: sgr:SGR_1958 putative catalase; PFAM: Catalase related subgroup; Catalase domain protein; Belongs to the catalase family.
  
  
 0.536
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.527
Tpau_0545
PFAM: Ferritin Dps family protein; KEGG: nfa:nfa43820 hypothetical protein; Belongs to the Dps family.
  
  
 0.504
Tpau_0406
PFAM: response regulator receiver; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rer:RER_40230 two-component system thioredoxin reductase; SMART: response regulator receiver.
  
  
 0.430
Tpau_2563
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
      
 0.424
Tpau_0126
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.423
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
  
  
 0.421
Tpau_3991
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; globin; KEGG: rop:ROP_19740 flavohemoprotein; Belongs to the globin family.
      
 0.411
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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