Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_3119TIGRFAM: fructose-1,6-bisphosphatase, class II; KEGG: rer:RER_42390 fructose 1,6-bisphosphatase class II; PFAM: GlpX family protein. (340 aa)    
Predicted Functional Partners:
Tpau_2522
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 0.966
Tpau_0511
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.946
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
    
 0.942
pgi
KEGG: rha:RHA1_ro05567 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family.
    
 0.935
pfkA
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
   
 
 0.930
Tpau_0185
1-phosphofructokinase; KEGG: mkm:Mkms_0090 ribokinase-like domain- containing protein; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
     
 0.910
Tpau_0525
PFAM: PfkB domain protein; KEGG: kse:Ksed_20450 sugar kinase, ribokinase.
    
 0.906
Tpau_3950
PFAM: Transketolase domain protein; KEGG: mno:Mnod_5660 transketolase domain protein.
 
   
  0.906
Tpau_1189
TIGRFAM: mannose-6-phosphate isomerase, class I; KEGG: mgi:Mflv_4724 mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I.
     
 0.901
Tpau_3949
PFAM: Transketolase domain protein; Transketolase central region; KEGG: rha:RHA1_ro00814 transketolase, C-terminal subunit.
     
  0.900
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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