| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Tpau_0695 | Tpau_1381 | Tpau_0695 | Tpau_1381 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rha:RHA1_ro02027 cysteine synthase. | PFAM: molybdopterin oxidoreductase; flavodoxin/nitric oxide synthase; FAD-binding domain protein; molybdopterin oxidoreductase Fe4S4 region; oxidoreductase FAD/NAD(P)-binding domain protein; molydopterin dinucleotide-binding region; KEGG: ppw:PputW619_1259 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.939 |
| Tpau_0695 | Tpau_2144 | Tpau_0695 | Tpau_2144 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rha:RHA1_ro02027 cysteine synthase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.866 |
| Tpau_0695 | Tpau_2771 | Tpau_0695 | Tpau_2771 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rha:RHA1_ro02027 cysteine synthase. | KEGG: rop:ROP_09710 sulfite reductase; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein. | 0.936 |
| Tpau_0695 | Tpau_3151 | Tpau_0695 | Tpau_3151 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rha:RHA1_ro02027 cysteine synthase. | KEGG: rha:RHA1_ro05845 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase. | 0.948 |
| Tpau_0695 | Tpau_3152 | Tpau_0695 | Tpau_3152 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rha:RHA1_ro02027 cysteine synthase. | TIGRFAM: cystathionine beta-synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; KEGG: rop:ROP_59040 cystathionine beta-synthase; SMART: CBS domain containing protein. | 0.815 |
| Tpau_0695 | Tpau_3390 | Tpau_0695 | Tpau_3390 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rha:RHA1_ro02027 cysteine synthase. | TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: rer:RER_20030 O-acetylhomoserine (thiol)- lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase. | 0.824 |
| Tpau_0695 | ahcY | Tpau_0695 | Tpau_1192 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rha:RHA1_ro02027 cysteine synthase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.836 |
| Tpau_0695 | metZ | Tpau_0695 | Tpau_0536 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rha:RHA1_ro02027 cysteine synthase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.948 |
| Tpau_1381 | Tpau_0695 | Tpau_1381 | Tpau_0695 | PFAM: molybdopterin oxidoreductase; flavodoxin/nitric oxide synthase; FAD-binding domain protein; molybdopterin oxidoreductase Fe4S4 region; oxidoreductase FAD/NAD(P)-binding domain protein; molydopterin dinucleotide-binding region; KEGG: ppw:PputW619_1259 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rha:RHA1_ro02027 cysteine synthase. | 0.939 |
| Tpau_1381 | Tpau_2144 | Tpau_1381 | Tpau_2144 | PFAM: molybdopterin oxidoreductase; flavodoxin/nitric oxide synthase; FAD-binding domain protein; molybdopterin oxidoreductase Fe4S4 region; oxidoreductase FAD/NAD(P)-binding domain protein; molydopterin dinucleotide-binding region; KEGG: ppw:PputW619_1259 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.827 |
| Tpau_1381 | Tpau_2771 | Tpau_1381 | Tpau_2771 | PFAM: molybdopterin oxidoreductase; flavodoxin/nitric oxide synthase; FAD-binding domain protein; molybdopterin oxidoreductase Fe4S4 region; oxidoreductase FAD/NAD(P)-binding domain protein; molydopterin dinucleotide-binding region; KEGG: ppw:PputW619_1259 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | KEGG: rop:ROP_09710 sulfite reductase; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein. | 0.986 |
| Tpau_1381 | Tpau_3151 | Tpau_1381 | Tpau_3151 | PFAM: molybdopterin oxidoreductase; flavodoxin/nitric oxide synthase; FAD-binding domain protein; molybdopterin oxidoreductase Fe4S4 region; oxidoreductase FAD/NAD(P)-binding domain protein; molydopterin dinucleotide-binding region; KEGG: ppw:PputW619_1259 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | KEGG: rha:RHA1_ro05845 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase. | 0.930 |
| Tpau_1381 | Tpau_3152 | Tpau_1381 | Tpau_3152 | PFAM: molybdopterin oxidoreductase; flavodoxin/nitric oxide synthase; FAD-binding domain protein; molybdopterin oxidoreductase Fe4S4 region; oxidoreductase FAD/NAD(P)-binding domain protein; molydopterin dinucleotide-binding region; KEGG: ppw:PputW619_1259 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | TIGRFAM: cystathionine beta-synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; KEGG: rop:ROP_59040 cystathionine beta-synthase; SMART: CBS domain containing protein. | 0.421 |
| Tpau_1381 | metZ | Tpau_1381 | Tpau_0536 | PFAM: molybdopterin oxidoreductase; flavodoxin/nitric oxide synthase; FAD-binding domain protein; molybdopterin oxidoreductase Fe4S4 region; oxidoreductase FAD/NAD(P)-binding domain protein; molydopterin dinucleotide-binding region; KEGG: ppw:PputW619_1259 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.930 |
| Tpau_1524 | Tpau_2144 | Tpau_1524 | Tpau_2144 | KEGG: mab:MAB_1950 branched-chain amino acid aminotransferase (IlvE); TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.557 |
| Tpau_1524 | Tpau_3151 | Tpau_1524 | Tpau_3151 | KEGG: mab:MAB_1950 branched-chain amino acid aminotransferase (IlvE); TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV. | KEGG: rha:RHA1_ro05845 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase. | 0.921 |
| Tpau_2144 | Tpau_0695 | Tpau_2144 | Tpau_0695 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rha:RHA1_ro02027 cysteine synthase. | 0.866 |
| Tpau_2144 | Tpau_1381 | Tpau_2144 | Tpau_1381 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: molybdopterin oxidoreductase; flavodoxin/nitric oxide synthase; FAD-binding domain protein; molybdopterin oxidoreductase Fe4S4 region; oxidoreductase FAD/NAD(P)-binding domain protein; molydopterin dinucleotide-binding region; KEGG: ppw:PputW619_1259 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.827 |
| Tpau_2144 | Tpau_1524 | Tpau_2144 | Tpau_1524 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: mab:MAB_1950 branched-chain amino acid aminotransferase (IlvE); TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV. | 0.557 |
| Tpau_2144 | Tpau_2771 | Tpau_2144 | Tpau_2771 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: rop:ROP_09710 sulfite reductase; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein. | 0.480 |