Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_3284PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: rop:ROP_56870 S1C family peptidase. (420 aa)    
Predicted Functional Partners:
Tpau_3283
PFAM: molybdopterin binding domain; KEGG: rha:RHA1_ro05625 molybdenum cofactor biosynthesis protein.
  
    0.949
Tpau_3285
Integral membrane sensor signal transduction histidine kinase; KEGG: rer:RER_43970 two-component histidine kinase MprB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
  
  
 0.833
Tpau_3282
KEGG: sen:SACE_0768 hypothetical protein.
       0.777
arc
AAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
    
 0.721
Tpau_1005
PFAM: Carbohydrate kinase, FGGY-like; KEGG: rop:ROP_63250 glycerol kinase.
   
 0.677
Tpau_0734
PFAM: peptidase M48 Ste24p; KEGG: sen:SACE_6884 protease HtpX-like protein.
  
  
 0.643
Tpau_3286
Two component transcriptional regulator, winged helix family; KEGG: rer:RER_43980 two-component response regulator MprA; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
  
  
 0.566
Tpau_1831
Iron (metal) dependent repressor, DtxR family; KEGG: nfa:nfa37790 putative transcriptional regulator; PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor.
  
    0.553
Tpau_2312
Phage shock protein C, PspC; PFAM: PspC domain protein; KEGG: rer:RER_48860 hypothetical protein.
  
  
 0.544
Tpau_0913
Phage shock protein C, PspC; PFAM: PspC domain protein; KEGG: nfa:nfa9000 hypothetical protein.
  
  
 0.536
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.