Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_3296Hypothetical protein; KEGG: vap:Vapar_0954 putative histone H1/H5 family protein, HCT subfamily. (360 aa)    
Predicted Functional Partners:
Tpau_4096
KEGG: mab:MAB_1644 hypothetical protein.
    
 0.686
Tpau_2325
PFAM: cytochrome b5; fatty acid desaturase; KEGG: nfa:nfa49300 hypothetical protein.
    
 0.680
Tpau_0407
Histidine kinase; KEGG: rer:RER_40240 two-component histidine kinase; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; SMART: ATP-binding region ATPase domain protein.
   
 0.665
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.650
Tpau_1832
Histone deacetylase; KEGG: rer:RER_28020 acetoin utilization protein; PFAM: histone deacetylase superfamily.
    
 0.647
Tpau_1913
PFAM: glycosyl transferase family 2; KEGG: rer:RER_18450 glycosyltransferase.
  
 
 0.641
Tpau_3297
PFAM: protein of unknown function DUF1707; KEGG: svi:Svir_05520 protein of unknown function (DUF1707).
       0.636
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.635
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.602
Tpau_1589
KEGG: lmc:Lm4b_00680 hypothetical protein.
  
 0.575
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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