Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_3326PFAM: Peptidase M23; KEGG: rer:RER_44310 hypothetical protein. (340 aa)    
Predicted Functional Partners:
Tpau_3939
Peptidoglycan glycosyltransferase; PFAM: glycosyl transferase family 51; PASTA domain containing protein; penicillin-binding protein transpeptidase; KEGG: rer:RER_04630 penicillin-binding protein 1; SMART: PASTA domain containing protein.
 
   
 0.646
Tpau_4192
Peptidoglycan glycosyltransferase; KEGG: nfa:nfa55570 putative penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin- binding protein transpeptidase.
  
   
 0.580
Tpau_0346
Neprilysin; KEGG: nfa:nfa56400 putative peptidase; PFAM: peptidase M13; Peptidase M13, neprilysin- like.
      
 0.535
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
 
   
 0.522
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
   
 0.484
Tpau_3325
KEGG: bln:Blon_0418 ABC transporter related; PFAM: ABC transporter related; ABC nitrate/sulphonate/bicarbonate family transporter, ATPase subunit; SMART: AAA ATPase.
       0.467
Tpau_3021
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
  
 0.455
Tpau_1631
TIGRFAM: signal peptidase I; KEGG: mmi:MMAR_1805 signal peptidase I LepB; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family.
 
  
 0.448
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
   
 0.448
secF
Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
   
 0.431
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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