Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_3476KEGG: stp:Strop_2778 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Acyl transferase; KR domain protein; Thioesterase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding. (2078 aa)    
Predicted Functional Partners:
Tpau_1315
PFAM: MaoC domain protein dehydratase; Beta- ketoacyl synthase; Acyl transferase; domain of unknown function DUF1729; KEGG: nfa:nfa12570 putative fatty acid synthase.
  
 0.998
Tpau_3480
Mycocerosate synthase., 6-deoxyerythronolide-B synthase; KEGG: sen:SACE_4141 type I modular polyketide synthase; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; KR domain protein; Acyl transferase; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding.
 
 
0.997
Tpau_3985
PFAM: MbtH domain protein; KEGG: mjl:Mjls_3474 MbtH domain-containing protein.
 
 
 0.996
Tpau_3693
Amino acid adenylation domain protein; KEGG: rop:ROP_20370 non-ribosomal peptide synthetase; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein.
 
 0.995
Tpau_3475
PFAM: Thioesterase; KEGG: fra:Francci3_2412 thioesterase.
  
 0.994
Tpau_3477
PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: sgr:SGR_6073 putative type-I PKS.
 
 
0.994
Tpau_3987
TIGRFAM: amino acid adenylation domain protein; daunorubicin resistance ABC transporter ATPase subunit; PFAM: AMP-dependent synthetase and ligase; Thioesterase; ABC transporter related; phosphopantetheine- binding; condensation domain protein; KEGG: rer:RER_30610 non-ribosomal peptide synthetase; SMART: AAA ATPase.
 
 0.994
Tpau_1373
Thioester reductase domain protein; KEGG: mab:MAB_2962 fatty-acid-CoA ligase FadD; TIGRFAM: thioester reductase domain protein; PFAM: Male sterility domain; AMP-dependent synthetase and ligase; phosphopantetheine-binding.
 
 
 0.991
Tpau_0175
PFAM: Beta-ketoacyl synthase; Acyl transferase; Thioesterase; phosphopantetheine-binding; KEGG: rha:RHA1_ro04065 polyketide synthase.
 
 
0.990
Tpau_1726
PFAM: 4'-phosphopantetheinyl transferase; KEGG: rer:RER_26380 phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
 
 
 0.988
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: medium (54%) [HD]