Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_3481PFAM: NDP-hexose 23-dehydratase; KEGG: svi:Svir_29870 NDP-hexose 2,3-dehydratase. (435 aa)    
Predicted Functional Partners:
Tpau_3482
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: stp:Strop_2218 oxidoreductase domain- containing protein.
 
  
 0.981
Tpau_3476
KEGG: stp:Strop_2778 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Acyl transferase; KR domain protein; Thioesterase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding.
 
  
 0.953
Tpau_3693
Amino acid adenylation domain protein; KEGG: rop:ROP_20370 non-ribosomal peptide synthetase; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein.
 
  
 0.926
Tpau_3787
KEGG: rer:RER_02500 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
    
  0.917
Tpau_0053
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
    
 0.909
Tpau_0057
KEGG: rop:ROP_39590 dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related.
    
 0.909
Tpau_3480
Mycocerosate synthase., 6-deoxyerythronolide-B synthase; KEGG: sen:SACE_4141 type I modular polyketide synthase; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; KR domain protein; Acyl transferase; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding.
 
  
 0.906
Tpau_3477
PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: sgr:SGR_6073 putative type-I PKS.
 
  
 0.865
Tpau_0175
PFAM: Beta-ketoacyl synthase; Acyl transferase; Thioesterase; phosphopantetheine-binding; KEGG: rha:RHA1_ro04065 polyketide synthase.
  
  
 0.855
Tpau_3483
PFAM: NAD-dependent epimerase/dehydratase; KEGG: rlt:Rleg2_0410 NAD-dependent epimerase/dehydratase.
 
   
 0.830
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.