Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Tpau_3487PFAM: protein of unknown function DUF1205; glycosyl transferase family 28; KEGG: sen:SACE_0726 glycosyl transferase, NDP-D- desosamine: 3-L-mycarosyl erythronolide B. (417 aa)    
Predicted Functional Partners:
Tpau_3480
Mycocerosate synthase., 6-deoxyerythronolide-B synthase; KEGG: sen:SACE_4141 type I modular polyketide synthase; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; KR domain protein; Acyl transferase; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding.
 
  
 0.782
Tpau_3477
PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: sgr:SGR_6073 putative type-I PKS.
 
  
 0.767
Tpau_3476
KEGG: stp:Strop_2778 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Acyl transferase; KR domain protein; Thioesterase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding.
 
  
 0.763
Tpau_3481
PFAM: NDP-hexose 23-dehydratase; KEGG: svi:Svir_29870 NDP-hexose 2,3-dehydratase.
 
   
 0.761
Tpau_3478
PFAM: Acyl transferase; short-chain dehydrogenase/reductase SDR; Beta-ketoacyl synthase; KR domain protein; Erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: sen:SACE_4141 type I modular polyketide synthase.
 
  
 0.719
Tpau_2335
TIGRFAM: glycosyltransferase, MGT family; KEGG: rha:RHA1_ro04832 glycosyltransferase; Belongs to the UDP-glycosyltransferase family.
  
     0.636
Tpau_3479
PFAM: Acyl transferase; Beta-ketoacyl synthase; phosphopantetheine-binding; KEGG: sma:SAV_943 type I polyketide synthase AVES 4.
 
  
 0.604
Tpau_3475
PFAM: Thioesterase; KEGG: fra:Francci3_2412 thioesterase.
 
   
 0.570
Tpau_0038
PFAM: flavoprotein; KEGG: fra:Francci3_1816 flavoprotein.
 
     0.496
Tpau_3693
Amino acid adenylation domain protein; KEGG: rop:ROP_20370 non-ribosomal peptide synthetase; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein.
 
  
 0.494
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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