Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_3516PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: mab:MAB_4052c putative lipase/esterase. (328 aa)    
Predicted Functional Partners:
Tpau_3513
PFAM: FAD dependent oxidoreductase; KEGG: nfa:nfa28620 putative monooxygenase.
  
 0.869
Tpau_3515
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: nfa:nfa28640 putative short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.864
Tpau_3514
KEGG: nfa:nfa28630 hypothetical protein.
 
     0.849
Tpau_3512
Transcriptional regulator, MerR family; KEGG: nfa:nfa28610 putative transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR.
 
     0.795
Tpau_3517
PFAM: Oxidoreductase FAD-binding domain protein; ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: mab:MAB_3918c putative oxidoreductase.
   
   0.631
Tpau_3476
KEGG: stp:Strop_2778 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Acyl transferase; KR domain protein; Thioesterase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding.
  
 
 0.521
Tpau_3444
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: rer:RER_34410 flavin-containing monooxygenase.
  
 0.466
Tpau_3480
Mycocerosate synthase., 6-deoxyerythronolide-B synthase; KEGG: sen:SACE_4141 type I modular polyketide synthase; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; KR domain protein; Acyl transferase; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding.
  
 
 0.443
Tpau_3685
PFAM: AMP-dependent synthetase and ligase; KEGG: rop:ROP_48840 2,3-dihydroxybenzoate-AMP ligase.
  
  
 0.413
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
   0.411
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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