Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_3533PFAM: histidine kinase dimerisation and phosphoacceptor region; KEGG: rer:RER_59600 two-component histidine kinase. (369 aa)    
Predicted Functional Partners:
Tpau_3534
KEGG: rer:RER_59590 NarL family two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 0.997
Tpau_3532
PFAM: ABC-2 type transporter; KEGG: cef:CE1020 hypothetical protein.
 
  
 0.909
Tpau_3531
KEGG: rer:RER_59620 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
 
     0.777
Tpau_0648
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: cms:CMS_1731 putative two component sensor kinase.
  
     0.714
Tpau_3530
Hypothetical protein.
       0.655
Tpau_2872
KEGG: rer:RER_23880 NarL family two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; Bacterio-opsin activator HTH domain protein; sigma-70 region 4 domain protein; SMART: regulatory protein LuxR; response regulator receiver.
 
 
 0.584
Tpau_1411
Integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; KEGG: rha:RHA1_ro05271 sensor kinase, two-component system.
  
     0.580
Tpau_3496
PFAM: ABC-2 type transporter; KEGG: rer:RER_47100 ABC transporter permease protein.
 
    0.574
Tpau_1009
Two component transcriptional regulator, LuxR family; KEGG: svi:Svir_39200 response regulator containing a CheY-like receiver domain protein and an HTH DNA-binding domain protein; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.531
Tpau_0972
KEGG: saq:Sare_0423 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR.
 
 
 0.529
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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