Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_3538Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake. (220 aa)    
Predicted Functional Partners:
Tpau_3541
KEGG: mab:MAB_4850c phosphate ABC transporter permease; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component.
 
  
 0.987
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
  
 0.983
Tpau_3542
Phosphate ABC transporter, inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
  
 0.905
Tpau_3543
Phosphate ABC transporter, periplasmic phosphate- binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
 
  
 0.837
Tpau_0653
Histidine kinase; KEGG: mab:MAB_4048c sensor-like histidine kinase senX3; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
  
 0.734
Tpau_3537
TIM-barrel protein, nifR3 family; KEGG: mmi:MMAR_4857 transcriptional regulator; TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS.
     
 0.683
Tpau_0107
KEGG: rop:ROP_35350 glutamate synthase large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II.
     
 0.596
Tpau_4018
PFAM: Alkaline phosphatase; KEGG: rer:RER_19780 alkaline phosphatase; SMART: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
  
 0.480
Tpau_3536
PFAM: fatty acid desaturase type 2; KEGG: nfa:nfa6080 putative fatty acid desaturase.
       0.425
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: low (26%) [HD]