Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_3543Phosphate ABC transporter, periplasmic phosphate- binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (374 aa)    
Predicted Functional Partners:
Tpau_3541
KEGG: mab:MAB_4850c phosphate ABC transporter permease; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component.
 
 0.999
Tpau_3542
Phosphate ABC transporter, inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 0.999
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
 0.998
Tpau_3538
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
 
  
 0.837
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.678
Tpau_3545
Putative two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain protein; KEGG: mab:MAB_0744 transcriptional regulatory protein.
  
  
 0.665
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
     
 0.642
Tpau_0653
Histidine kinase; KEGG: mab:MAB_4048c sensor-like histidine kinase senX3; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
  
  
 0.605
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
     
 0.597
Tpau_4018
PFAM: Alkaline phosphatase; KEGG: rer:RER_19780 alkaline phosphatase; SMART: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
  
 0.563
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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