Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_3597Response regulator receiver and unknown domain protein; KEGG: rha:RHA1_ro04820 regulator relate; PFAM: response regulator receiver; SMART: response regulator receiver. (228 aa)    
Predicted Functional Partners:
Tpau_3596
Signal transduction histidine kinase regulating citrate/malate metabolism; KEGG: nfa:nfa46340 putative two-component system sensor kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 
 0.974
Tpau_1350
Signal transduction histidine kinase regulating citrate/malate metabolism; KEGG: cmi:CMM_2877 putative two-component system, sensor kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
 
 
 0.890
Tpau_3595
PFAM: sodium:dicarboxylate symporter; KEGG: nfa:nfa46330 putative sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
 
   
 0.732
Tpau_3591
PFAM: amino acid permease-associated region; KEGG: pac:PPA2254 amino acid permease, putative GabA permease.
       0.405
purL
Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]
       0.400
cysC-2
Sulfate adenylyltransferase, large subunit; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.
       0.400
Tpau_3594
TIGRFAM: sulfate adenylyltransferase, small subunit; KEGG: mab:MAB_4181 sulfate adenylyltransferase subunit 2; PFAM: phosphoadenosine phosphosulfate reductase.
       0.400
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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