Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_3640PFAM: protein of unknown function DUF1212; KEGG: rop:ROP_48160 threonine export protein. (467 aa)    
Predicted Functional Partners:
Tpau_3642
KEGG: rer:RER_09680 alpha,alpha-trehalose-phosphate synthase; PFAM: glycosyl transferase family 20.
       0.774
Tpau_3643
Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
       0.774
Tpau_3641
KEGG: rop:ROP_48070 hypothetical protein.
       0.769
Tpau_3639
Hypothetical protein.
       0.553
Tpau_2566
PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: rop:ROP_69450 putative rRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
       0.453
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
     0.453
Tpau_2132
KEGG: rer:RER_32090 hypothetical protein.
 
     0.451
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
       0.438
Tpau_0674
PFAM: Heavy metal transport/detoxification protein; KEGG: svi:Svir_36750 copper chaperone.
     
 0.437
Tpau_0027
KEGG: rer:RER_00280 serine/threonine protein kinase PknB; PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein.
       0.436
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.