Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_3681PFAM: protein of unknown function DUF344; KEGG: mab:MAB_4135c hypothetical protein. (311 aa)    
Predicted Functional Partners:
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
  
 0.971
Tpau_3680
KEGG: mav:MAV_4699 hypothetical protein.
       0.710
Tpau_3679
PFAM: alpha/beta hydrolase fold; KEGG: rop:ROP_18600 hypothetical protein.
       0.654
Tpau_0656
PFAM: Ppx/GppA phosphatase; KEGG: mab:MAB_4013c hypothetical protein.
 
  
 0.635
Tpau_3682
PFAM: regulatory protein TetR; KEGG: bte:BTH_II1794 transcriptional regulator.
     
 0.556
Tpau_3162
PFAM: Ppx/GppA phosphatase; KEGG: mab:MAB_1168 hypothetical protein.
 
  
 0.518
Tpau_1085
KEGG: mab:MAB_3550c hypothetical protein.
     
 0.503
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
      
 0.463
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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