STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Tpau_3747KEGG: mgi:Mflv_0196 sulfur carrier protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein. (65 aa)    
Predicted Functional Partners:
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.998
Tpau_1123
UBA/THIF-type NAD/FAD binding protein; KEGG: mab:MAB_3525c molybdenum cofactor biosynthesis protein MoeB1; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein.
  
 
 0.945
Tpau_3748
Glycine oxidase ThiO; KEGG: nfa:nfa53390 putative amino acid oxidase; TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase.
 
  
 0.943
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.935
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.867
Tpau_3041
KEGG: nfa:nfa45300 hypothetical protein.
  
 
 0.807
Tpau_1148
TIGRFAM: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; 7,8-didemethyl-8-hydroxy-5- deazariboflavin synthase, CofG subunit; PFAM: Radical SAM domain protein; KEGG: rop:ROP_60060 7,8-didemethyl-8-hydroxy-5- deazariboflavine synthase; SMART: Elongator protein 3/MiaB/NifB.
  
  
 0.783
Tpau_1289
Mov34/MPN/PAD-1 family protein; KEGG: sen:SACE_1204 Mov34/MPN/PAD-1; PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein.
  
 
 0.780
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
 
 0.748
Tpau_3738
TIGRFAM: phosphomethylpyrimidine kinase; KEGG: rop:ROP_18980 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
  
    0.680
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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