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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (222 aa)    
Predicted Functional Partners:
Tpau_3738
TIGRFAM: phosphomethylpyrimidine kinase; KEGG: rop:ROP_18980 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
 
 0.998
Tpau_3739
KEGG: msm:MSMEG_0825 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
 
 0.998
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.996
Tpau_3747
KEGG: mgi:Mflv_0196 sulfur carrier protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein.
  
  
 0.948
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.933
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
  
 
 0.932
Tpau_1096
GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
     
 0.905
Tpau_4018
PFAM: Alkaline phosphatase; KEGG: rer:RER_19780 alkaline phosphatase; SMART: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
    
  0.901
Tpau_1148
TIGRFAM: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; 7,8-didemethyl-8-hydroxy-5- deazariboflavin synthase, CofG subunit; PFAM: Radical SAM domain protein; KEGG: rop:ROP_60060 7,8-didemethyl-8-hydroxy-5- deazariboflavine synthase; SMART: Elongator protein 3/MiaB/NifB.
  
  
 0.887
Tpau_1123
UBA/THIF-type NAD/FAD binding protein; KEGG: mab:MAB_3525c molybdenum cofactor biosynthesis protein MoeB1; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein.
 
  
 0.865
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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