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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (386 aa)    
Predicted Functional Partners:
Tpau_3762
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
 
 0.999
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.945
Tpau_0284
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: msm:MSMEG_3964 pyruvate dehydrogenase; Belongs to the TPP enzyme family.
    
 0.940
Tpau_3071
PFAM: AMP-dependent synthetase and ligase; KEGG: ami:Amir_2275 AMP-dependent synthetase and ligase.
     
 0.937
Tpau_1571
PFAM: acylphosphatase; KEGG: nfa:nfa41730 putative acylphosphatase.
     
 0.917
Tpau_3668
KEGG: mab:MAB_4095c isocitrate lyase (AceA); TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase.
   
  
 0.915
Tpau_2996
PFAM: coenzyme A transferase; KEGG: tmz:Tmz1t_0549 coenzyme A transferase.
     
 0.911
Tpau_2035
PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein.
    
 0.910
Tpau_2282
KEGG: mab:MAB_2126 putative L-lactate 2- monooxygenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase.
     
 0.906
Tpau_2671
PFAM: AMP-dependent synthetase and ligase; KEGG: svi:Svir_32550 acyl-CoA synthetase/AMP-acid ligase.
     
 0.906
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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