| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Tpau_1517 | Tpau_2035 | Tpau_1517 | Tpau_2035 | KEGG: nfa:nfa16900 dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein. | PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein. | 0.905 |
| Tpau_1517 | Tpau_3071 | Tpau_1517 | Tpau_3071 | KEGG: nfa:nfa16900 dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein. | PFAM: AMP-dependent synthetase and ligase; KEGG: ami:Amir_2275 AMP-dependent synthetase and ligase. | 0.907 |
| Tpau_1517 | Tpau_3668 | Tpau_1517 | Tpau_3668 | KEGG: nfa:nfa16900 dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein. | KEGG: mab:MAB_4095c isocitrate lyase (AceA); TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase. | 0.824 |
| Tpau_1517 | Tpau_3762 | Tpau_1517 | Tpau_3762 | KEGG: nfa:nfa16900 dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.959 |
| Tpau_1517 | Tpau_3801 | Tpau_1517 | Tpau_3801 | KEGG: nfa:nfa16900 dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein. | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.900 |
| Tpau_1517 | acsA | Tpau_1517 | Tpau_3916 | KEGG: nfa:nfa16900 dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein. | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.907 |
| Tpau_1517 | glcB | Tpau_1517 | Tpau_2328 | KEGG: nfa:nfa16900 dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.910 |
| Tpau_1571 | Tpau_2035 | Tpau_1571 | Tpau_2035 | PFAM: acylphosphatase; KEGG: nfa:nfa41730 putative acylphosphatase. | PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein. | 0.900 |
| Tpau_1571 | Tpau_3071 | Tpau_1571 | Tpau_3071 | PFAM: acylphosphatase; KEGG: nfa:nfa41730 putative acylphosphatase. | PFAM: AMP-dependent synthetase and ligase; KEGG: ami:Amir_2275 AMP-dependent synthetase and ligase. | 0.903 |
| Tpau_1571 | Tpau_3762 | Tpau_1571 | Tpau_3762 | PFAM: acylphosphatase; KEGG: nfa:nfa41730 putative acylphosphatase. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.942 |
| Tpau_1571 | ackA | Tpau_1571 | Tpau_3761 | PFAM: acylphosphatase; KEGG: nfa:nfa41730 putative acylphosphatase. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.917 |
| Tpau_1571 | acsA | Tpau_1571 | Tpau_3916 | PFAM: acylphosphatase; KEGG: nfa:nfa41730 putative acylphosphatase. | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.903 |
| Tpau_2035 | Tpau_1517 | Tpau_2035 | Tpau_1517 | PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein. | KEGG: nfa:nfa16900 dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein. | 0.905 |
| Tpau_2035 | Tpau_1571 | Tpau_2035 | Tpau_1571 | PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein. | PFAM: acylphosphatase; KEGG: nfa:nfa41730 putative acylphosphatase. | 0.900 |
| Tpau_2035 | Tpau_2671 | Tpau_2035 | Tpau_2671 | PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein. | PFAM: AMP-dependent synthetase and ligase; KEGG: svi:Svir_32550 acyl-CoA synthetase/AMP-acid ligase. | 0.923 |
| Tpau_2035 | Tpau_3071 | Tpau_2035 | Tpau_3071 | PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein. | PFAM: AMP-dependent synthetase and ligase; KEGG: ami:Amir_2275 AMP-dependent synthetase and ligase. | 0.906 |
| Tpau_2035 | Tpau_3668 | Tpau_2035 | Tpau_3668 | PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein. | KEGG: mab:MAB_4095c isocitrate lyase (AceA); TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase. | 0.807 |
| Tpau_2035 | Tpau_3762 | Tpau_2035 | Tpau_3762 | PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.933 |
| Tpau_2035 | Tpau_3801 | Tpau_2035 | Tpau_3801 | PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein. | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.900 |
| Tpau_2035 | ackA | Tpau_2035 | Tpau_3761 | PFAM: CoA-binding domain protein; KEGG: tmz:Tmz1t_0645 CoA-binding domain protein. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.910 |