Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_3769PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: mab:MAB_0484 putative hydrolase/esterase/lipase. (329 aa)    
Predicted Functional Partners:
Tpau_0082
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: ami:Amir_0226 alpha/beta hydrolase fold-3 domain protein.
  
   
 0.775
Tpau_2931
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: rha:RHA1_ro03099 esterase/lipase.
  
   
 0.756
Tpau_3770
KEGG: rer:RER_05430 non-ribosomal peptide synthetase; TIGRFAM: non-ribosomal peptide synthetase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; transferase hexapeptide repeat containing protein; phosphopantetheine-binding.
  
 
 0.618
Tpau_3476
KEGG: stp:Strop_2778 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Acyl transferase; KR domain protein; Thioesterase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding.
  
 
 0.521
Tpau_3768
Hypothetical protein.
       0.495
Tpau_3480
Mycocerosate synthase., 6-deoxyerythronolide-B synthase; KEGG: sen:SACE_4141 type I modular polyketide synthase; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; KR domain protein; Acyl transferase; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding.
  
 
 0.443
Tpau_3513
PFAM: FAD dependent oxidoreductase; KEGG: nfa:nfa28620 putative monooxygenase.
 
  
 0.415
Tpau_3685
PFAM: AMP-dependent synthetase and ligase; KEGG: rop:ROP_48840 2,3-dihydroxybenzoate-AMP ligase.
  
  
 0.413
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
   0.411
Tpau_0175
PFAM: Beta-ketoacyl synthase; Acyl transferase; Thioesterase; phosphopantetheine-binding; KEGG: rha:RHA1_ro04065 polyketide synthase.
  
 
 0.406
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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