Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_3786Putative RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: nca:Noca_2117 sigma-70 region 2 domain- containing protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2. (422 aa)    
Predicted Functional Partners:
Tpau_3785
KEGG: nca:Noca_2116 DGPFAETKE family protein.
 
    0.841
Tpau_3086
PFAM: YCII-related; KEGG: krh:KRH_21960 hypothetical protein.
 
    0.784
Tpau_0813
PFAM: YCII-related; KEGG: nca:Noca_0396 DGPFAETKE family protein.
 
    0.781
Tpau_2593
PFAM: YCII-related; KEGG: nca:Noca_0396 DGPFAETKE family protein.
 
    0.781
Tpau_3787
KEGG: rer:RER_02500 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
     
 0.646
Tpau_3784
Putative transcriptional regulator, PaaX family; PFAM: PaaX domain protein domain; KEGG: mab:MAB_0920 putative repressor in the phenylacetic acid catabolism.
       0.444
Tpau_3788
PFAM: regulatory protein TetR; KEGG: mjl:Mjls_5098 TetR family transcriptional regulator.
       0.424
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.