Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_3844PFAM: alpha/beta hydrolase fold; KEGG: rop:ROP_44550 MetA-cleavage compound hydrolase. (289 aa)    
Predicted Functional Partners:
Tpau_3843
Biphenyl-2,3-diol 1,2-dioxygenase; KEGG: mab:MAB_0585 2,3-dihydroxybiphenyl 1,2- dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
 
 0.995
Tpau_3845
PFAM: Acyl-CoA dehydrogenase type 2 domain; KEGG: rop:ROP_44540 putative hydroxylase.
 
 0.962
Tpau_3836
PFAM: AMP-dependent synthetase and ligase; KEGG: rop:ROP_45400 putative fatty-acid--CoA ligase.
  
  0.919
Tpau_3849
Rieske (2Fe-2S) iron-sulfur domain protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; KEGG: rha:RHA1_ro04538 ketosteroid-9-alpha- hydroxylase, oxygenase.
 
 
 
 0.798
Tpau_3842
PFAM: flavin reductase domain protein FMN-binding; KEGG: rer:RER_07580 oxidoreductase.
 
  
 0.797
Tpau_3846
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: nfa:nfa46590 hypothetical protein.
 
     0.707
Tpau_3850
KEGG: saq:Sare_2881 hypothetical protein.
 
     0.696
Tpau_3848
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: rer:RER_07370 3-keto-5alpha-steroid delta(1)- dehydrogenase KstD3.
 
   
 0.685
Tpau_3800
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.661
Tpau_3837
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: nfa:nfa4820 enoyl-CoA hydratase.
  
 
  0.634
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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