Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Tpau_3871PFAM: bifunctional deaminase-reductase domain protein; KEGG: ami:Amir_5078 bifunctional deaminase- reductase domain protein. (180 aa)    
Predicted Functional Partners:
Tpau_3872
Hypothetical protein; KEGG: rrs:RoseRS_2673 pyridoxamine 5'-phosphate oxidase-related, FMN-binding.
       0.773
Tpau_3158
PFAM: bifunctional deaminase-reductase domain protein; KEGG: sco:SCO2813 hypothetical protein.
 
     0.723
Tpau_2516
PFAM: bifunctional deaminase-reductase domain protein; KEGG: aau:AAur_0663 riboflavin biosynthesis protein RibD.
 
     0.594
Tpau_1910
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ach:Achl_3375 glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.544
Tpau_3873
KEGG: mkm:Mkms_4403 protein kinase; PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase.
  
    0.525
Tpau_3870
KEGG: nfa:nfa12780 putative monooxygenase.
       0.513
Tpau_1051
KEGG: ach:Achl_0378 bifunctional deaminase- reductase domain protein.
 
     0.512
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.495
Tpau_0787
PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: fre:Franean1_4113 activator of HSP90 ATPase 1 family protein.
 
     0.431
Tpau_3869
Putative transcriptional regulator, PucR family; KEGG: sma:SAV_1389 hypothetical protein.
 
     0.413
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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