STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpau_3875Adenylate/guanylate cyclase with integral membrane sensor; KEGG: mva:Mvan_5395 putative adenylate/guanylate cyclase; PFAM: histidine kinase HAMP region domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; histidine kinase HAMP region domain protein. (499 aa)    
Predicted Functional Partners:
Tpau_2734
Adenylate/guanylate cyclase; KEGG: nfa:nfa53340 hypothetical protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
  
  
 0.972
Tpau_0212
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mab:MAB_4771 putative adenylate cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
  
  
 0.945
Tpau_3760
Adenylate/guanylate cyclase with integral membrane sensor; KEGG: rop:ROP_11720 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; adenylyl cyclase class-3/4/guanylyl cyclase.
  
  
 
0.915
Tpau_0786
Adenylate/guanylate cyclase with integral membrane sensor; KEGG: mab:MAB_1459c hypothetical protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; adenylyl cyclase class-3/4/guanylyl cyclase.
  
  
 
0.913
Tpau_2490
TIGRFAM: pyruvate kinase; KEGG: rha:RHA1_ro01007 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
    
 0.908
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.904
Tpau_1945
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.901
Tpau_0675
KEGG: mva:Mvan_0658 hypothetical protein.
     
  0.900
Tpau_2670
PFAM: RelA/SpoT domain protein; KEGG: jde:Jden_0358 RelA/SpoT domain protein.
     
 0.900
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
   
 0.816
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.