Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
whiB-5Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (103 aa)    
Predicted Functional Partners:
Tpau_1334
Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
    0.705
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.705
Tpau_2336
Transcriptional regulator, MerR family; SMART: regulatory protein MerR; KEGG: mab:MAB_2406 putative HTH-type transcriptional regulator.
  
     0.670
Tpau_1633
PFAM: Protein of unknown function DUF2469; KEGG: rop:ROP_65970 hypothetical protein.
  
     0.664
Tpau_3939
Peptidoglycan glycosyltransferase; PFAM: glycosyl transferase family 51; PASTA domain containing protein; penicillin-binding protein transpeptidase; KEGG: rer:RER_04630 penicillin-binding protein 1; SMART: PASTA domain containing protein.
   
 
 0.613
whiB
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
 
   
 0.594
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
  
  
 0.578
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.566
Tpau_2811
PFAM: cyclase/dehydrase; KEGG: rop:ROP_67300 hypothetical protein.
  
     0.496
Tpau_2801
PFAM: DNA polymerase III delta; KEGG: nfa:nfa13940 hypothetical protein.
 
     0.490
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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