Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tpau_4131PFAM: BioY protein; KEGG: lxx:Lxx20880 biotin synthase. (189 aa)    
Predicted Functional Partners:
Tpau_4129
PFAM: cobalt transport protein; KEGG: sen:SACE_1190 cobalt transport system permease protein.
 
 0.998
Tpau_4130
ABC transporter related protein; KEGG: tfu:Tfu_2313 ABC-type cobalt transport system ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
 0.998
Tpau_2487
KEGG: mpa:MAP3132 hypothetical protein; PFAM: ABC transporter related; cobalt transport protein; SMART: AAA ATPase.
  
 
 0.848
Tpau_4132
Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: nfa:nfa18310 putative transcriptional regulator.
 
   
 0.678
Tpau_1044
KEGG: mva:Mvan_1722 biotin--acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein.
 
   
 0.633
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
  
 0.573
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.556
Tpau_0860
PFAM: carboxyl transferase; KEGG: rer:RER_45670 acetyl-CoA carboxylase beta chain.
 
   
 0.544
Tpau_2193
TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; KEGG: nfa:nfa52820 3-oxoacyl-(acyl carrier protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier- protein (ACP)] synthase III; Belongs to the thiolase-like superfamily. FabH family.
 
   
 0.498
Tpau_1315
PFAM: MaoC domain protein dehydratase; Beta- ketoacyl synthase; Acyl transferase; domain of unknown function DUF1729; KEGG: nfa:nfa12570 putative fatty acid synthase.
     
 0.490
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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