Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Tpau_4181PFAM: AMP-dependent synthetase and ligase; KEGG: msm:MSMEG_0131 acyl-CoA synthetase. (527 aa)    
Predicted Functional Partners:
Tpau_3480
Mycocerosate synthase., 6-deoxyerythronolide-B synthase; KEGG: sen:SACE_4141 type I modular polyketide synthase; PFAM: short-chain dehydrogenase/reductase SDR; Beta- ketoacyl synthase; KR domain protein; Acyl transferase; NAD-dependent epimerase/dehydratase; phosphopantetheine- binding.
  
 0.930
Tpau_3476
KEGG: stp:Strop_2778 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Acyl transferase; KR domain protein; Thioesterase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding.
  
 0.867
Tpau_3477
PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; phosphopantetheine-binding; KEGG: sgr:SGR_6073 putative type-I PKS.
  
 0.837
Tpau_0175
PFAM: Beta-ketoacyl synthase; Acyl transferase; Thioesterase; phosphopantetheine-binding; KEGG: rha:RHA1_ro04065 polyketide synthase.
  
 0.757
Tpau_3478
PFAM: Acyl transferase; short-chain dehydrogenase/reductase SDR; Beta-ketoacyl synthase; KR domain protein; Erythronolide synthase docking; phosphopantetheine-binding; NAD-dependent epimerase/dehydratase; KEGG: sen:SACE_4141 type I modular polyketide synthase.
  
 0.716
Tpau_4182
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: svi:Svir_30250 acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.603
Tpau_4183
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: mab:MAB_0851 fatty oxidation protein FadB.
  
 
 0.593
Tpau_3838
PFAM: acyl-CoA dehydrogenase domain protein; KEGG: nfa:nfa4810 putative acyl-CoA dehydrogenase.
   
 
 0.574
Tpau_3839
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: mab:MAB_0594c acyl-CoA dehydrogenase FadE.
   
 
 0.571
Tpau_3855
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: nca:Noca_2790 acyl-CoA dehydrogenase domain- containing protein.
   
 
 0.533
Your Current Organism:
Tsukamurella paurometabola
NCBI taxonomy Id: 521096
Other names: T. paurometabola DSM 20162, Tsukamurella paurometabola ATCC 8368, Tsukamurella paurometabola DSM 20162, Tsukamurella paurometabola str. DSM 20162, Tsukamurella paurometabola strain DSM 20162
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