Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Coch_0080KEGG: gfo:GFO_0074 hypothetical protein. (177 aa)    
Predicted Functional Partners:
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.787
Coch_0608
KEGG: fps:FP0181 hypothetical protein.
  
     0.772
Coch_2120
KEGG: fps:FP2472 hypothetical protein.
  
     0.758
Coch_1728
KEGG: gfo:GFO_1569 secreted protein.
  
     0.753
Coch_0078
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.750
Coch_1243
KEGG: gfo:GFO_3541 conserved hypothetical protein, secreted.
  
     0.735
Coch_1791
KEGG: fjo:Fjoh_3471 hypothetical protein.
  
     0.731
Coch_0033
PFAM: Hyalin; KEGG: fjo:Fjoh_0979 hypothetical protein.
  
     0.724
Coch_1201
KEGG: gfo:GFO_1792 hypothetical protein.
  
     0.724
Coch_1447
PFAM: Sporulation domain protein; KEGG: fps:FP0015 putative cell surface protein precursor SprD.
  
     0.723
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
Server load: low (10%) [HD]