Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Coch_0087PFAM: aminotransferase class I and II; KEGG: bfs:BF0911 putative aminotransferase. (389 aa)    
Predicted Functional Partners:
Coch_1685
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: cac:CAC0390 cystathionine gamma-synthase.
 
 
 0.965
Coch_1623
PFAM: aminotransferase class I and II; KEGG: fps:FP1696 aspartate aminotransferase.
 
  
0.916
Coch_2047
PFAM: aminotransferase class I and II; KEGG: fps:FP0412 aspartate transaminase AspC1.
 
  
0.916
Coch_1822
TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: fjo:Fjoh_4653 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.915
Coch_1829
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gfo:GFO_1794 cysteine synthase/cystathionine beta-synthase.
    
 0.915
metE
5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
    
 0.908
Coch_1216
Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
 0.902
Coch_0944
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: fnu:FN1411 threonine dehydratase.
 
  
  0.834
Coch_0411
KEGG: fjo:Fjoh_1494 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; aspartate/glutamate/uridylate kinase.
    
 0.832
Coch_2053
KEGG: fjo:Fjoh_2400 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase dimerisation domain protein; peptidase M20.
    
  0.807
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
Server load: low (16%) [HD]