Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Coch_0145PFAM: integrase family protein; KEGG: pgn:PGN_0094 putative bacteriophage integrase; Belongs to the 'phage' integrase family. (411 aa)    
Predicted Functional Partners:
Coch_0342
KEGG: bfs:BF2755 hypothetical protein.
  
     0.643
Coch_0344
KEGG: bfs:BF2755 hypothetical protein.
  
     0.619
Coch_0343
KEGG: fjo:Fjoh_0107 hypothetical protein.
  
     0.617
Coch_1381
KEGG: gfo:GFO_3532 phosphoribosyltransferases family protein.
   
    0.614
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.611
Coch_1429
PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: gfo:GFO_0342 prephenate dehydrogenase.
  
    0.553
Coch_0611
PFAM: GCN5-related N-acetyltransferase; KEGG: fjo:Fjoh_3310 GCN5-related N- acetyltransferase.
  
     0.479
Coch_0220
Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid.
 
  
 0.467
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.456
Coch_0144
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: fjo:Fjoh_1507 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.431
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
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