Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
macBABC transporter related; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (226 aa)    
Predicted Functional Partners:
Coch_0390
PFAM: protein of unknown function DUF214; KEGG: bfs:BF1933 putative permease component of ABC transporter.
 
 0.987
Coch_1555
PFAM: protein of unknown function DUF214; KEGG: fjo:Fjoh_1460 hypothetical protein.
 
 0.972
Coch_1780
PFAM: protein of unknown function DUF214; KEGG: fps:FP2022 ABC transporter permease.
 
 0.962
Coch_0176
PFAM: glycosyl transferase family 2; KEGG: fjo:Fjoh_0448 glycosyl transferase family protein.
   
   0.781
Coch_0174
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.773
Coch_0463
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: fjo:Fjoh_1672 RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.747
Coch_0778
PFAM: protein of unknown function DUF214; KEGG: fps:FP0239 ABC transporter permease.
  
 
 0.721
Coch_2125
PFAM: protein of unknown function DUF214; KEGG: gfo:GFO_2398 lipoprotein releasing system transmembrane protein.
  
 
 0.721
Coch_0385
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: pdi:BDI_3353 periplasmic component of efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.714
nusG
NusG antitermination factor; Participates in transcription elongation, termination and antitermination.
      
 0.618
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
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