Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Coch_0209Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: gfo:GFO_0658 two-component system response regulator. (251 aa)    
Predicted Functional Partners:
Coch_0208
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: gfo:GFO_0657 two-component system sensor histidine kinase.
 
 0.953
Coch_1190
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: fjo:Fjoh_0937 histidine kinase.
  
 
 
 0.665
Coch_1826
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: fjo:Fjoh_0637 histidine kinase.
 
   0.639
Coch_1562
Histidine kinase; PFAM: response regulator receiver; Two component regulator three Y domain protein; Two component regulator propeller; ATP-binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bfr:BF4234 two-component system sensor histidine kinase/response regulator hybrid.
 
 
0.619
Coch_0220
Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid.
  
 
 0.617
Coch_1450
PFAM: histidine kinase A domain protein; ATP- binding region ATPase domain protein; SMART: histidine kinase A domain protein; ATP- binding region ATPase domain protein; KEGG: chu:CHU_3533 two-component sensor histidine kinase.
 
   0.571
Coch_1010
Histidine kinase; PFAM: response regulator receiver; Two component regulator three Y domain protein; Two component regulator propeller; ATP-binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: gfo:GFO_1697 two-component system sensor histidine kinase/response regulator hybrid.
  
 
 0.513
Coch_1470
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Two component regulator three Y domain protein; Two component regulator propeller; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: fjo:Fjoh_3862 histidine kinase.
  
 
 0.513
Coch_0353
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
 
 0.455
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.441
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
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