Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Coch_0302PFAM: histidine triad (HIT) protein; KEGG: fjo:Fjoh_1591 histidine triad (HIT) protein. (128 aa)    
Predicted Functional Partners:
Coch_1947
PFAM: helicase domain protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicases; KEGG: pmo:Pmob_1535 helicase domain-containing protein.
   
 
 0.721
cobB
PFAM: Silent information regulator protein Sir2; KEGG: fjo:Fjoh_5013 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
  
 
  0.699
Coch_0303
Hypothetical protein.
       0.675
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
     
 0.647
Coch_2005
TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: gfo:GFO_0812 uridine kinase.
   
  0.631
lysS
TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: gfo:GFO_2926 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 0.498
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
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