Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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xerCTyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (303 aa)    
Predicted Functional Partners:
Coch_0336
PFAM: cell divisionFtsK/SpoIIIE; KEGG: fjo:Fjoh_2112 cell divisionFtsK/SpoIIIE.
 
   
 0.645
Coch_1381
KEGG: gfo:GFO_3532 phosphoribosyltransferases family protein.
  
    0.626
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.611
Coch_0380
PFAM: DoxX family protein; KEGG: gfo:GFO_0431 conserved hypothetical protein, membrane.
       0.572
Coch_0379
PFAM: protein of unknown function DUF1599; KEGG: gfo:GFO_0430 protein containing DUF1599.
       0.553
Coch_1429
PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: gfo:GFO_0342 prephenate dehydrogenase.
  
    0.553
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.455
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
   
 0.435
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
    
 
 0.405
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
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