Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Coch_0437PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: fjo:Fjoh_1190 peptidase S8 and S53, subtilisin, kexin, sedolisin; Belongs to the peptidase S8 family. (517 aa)    
Predicted Functional Partners:
Coch_1241
PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: fjo:Fjoh_1191 peptidase M1, membrane alanine aminopeptidase.
 
  
 0.595
Coch_1221
TIGRFAM: calcium-translocating P-type ATPase, PMCA- type; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: amu:Amuc_0218 calcium-translocating P-type ATPase, PMCA-type.
   
 
 0.490
Coch_0336
PFAM: cell divisionFtsK/SpoIIIE; KEGG: fjo:Fjoh_2112 cell divisionFtsK/SpoIIIE.
  
 
 0.476
Coch_0435
PFAM: transcriptional regulator PadR family protein; KEGG: fjo:Fjoh_0195 PadR-like family transcriptional regulator.
  
    0.449
Coch_0436
Phage shock protein C, PspC; PFAM: PspC domain protein; KEGG: gfo:GFO_0991 membrane protein containing PspC domain.
       0.449
Coch_1258
KEGG: gfo:GFO_2891 conserved hypothetical protein, secreted.
   
   0.445
Coch_0220
Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid.
  
  
 0.438
Coch_1444
PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; peptidylprolyl isomerase FKBP-type; KEGG: fps:FP1908 peptidyl-prolyl cis-trans isomerase PpiC.
  
 
 0.421
Coch_1854
PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; peptidylprolyl isomerase FKBP-type; KEGG: gfo:GFO_0786 cyclophilin/FKBP-type peptidyl- prolyl cis-trans isomerase.
  
 
 0.421
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.413
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
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