Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Coch_0663TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: fjo:Fjoh_0995 DNA protecting protein DprA. (364 aa)    
Predicted Functional Partners:
Coch_2101
TIGRFAM: ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: fps:FP2334 hypothetical protein.
 
  
 0.895
Coch_1381
KEGG: gfo:GFO_3532 phosphoribosyltransferases family protein.
 
 
 0.889
Coch_1890
Mg chelatase, subunit ChlI; KEGG: fps:FP1610 hypothetical protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
 
 0.844
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.634
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.631
Coch_0917
TIGRFAM: DNA repair protein RadC; PFAM: DNA repair protein RadC; KEGG: gfo:GFO_2860 DNA repair protein RadC; Belongs to the UPF0758 family.
  
  
 0.581
Coch_0399
PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; KEGG: fjo:Fjoh_3187 alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
    0.576
Coch_0729
KEGG: fps:FP1192 hypothetical protein.
 
  
 0.542
Coch_0979
TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: fps:FP1664 single-strand DNA-binding protein ssb.
 
  
 0.522
Coch_2025
PFAM: protein of unknown function UPF0102; KEGG: fps:FP0059 hypothetical protein; Belongs to the UPF0102 family.
 
  
 0.510
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
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