| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Coch_0220 | Coch_1285 | Coch_0220 | Coch_1285 | Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid. | Alpha-glucan phosphorylase; KEGG: sat:SYN_00879 glycogen synthase/glycogen phosphorylase; TIGRFAM: alpha-glucan phosphorylase; PFAM: glycogen synthase; glycosyl transferase family 35. | 0.446 |
| Coch_0220 | Coch_1562 | Coch_0220 | Coch_1562 | Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid. | Histidine kinase; PFAM: response regulator receiver; Two component regulator three Y domain protein; Two component regulator propeller; ATP-binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bfr:BF4234 two-component system sensor histidine kinase/response regulator hybrid. | 0.995 |
| Coch_0220 | Coch_1947 | Coch_0220 | Coch_1947 | Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid. | PFAM: helicase domain protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicases; KEGG: pmo:Pmob_1535 helicase domain-containing protein. | 0.500 |
| Coch_0220 | glmS | Coch_0220 | Coch_1372 | Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid. | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.408 |
| Coch_0220 | groL | Coch_0220 | Coch_0317 | Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.629 |
| Coch_0220 | nnrD | Coch_0220 | Coch_1065 | Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.630 |
| Coch_0467 | Coch_1651 | Coch_0467 | Coch_1651 | PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: gfo:GFO_1099 DeaD-like DEAD box family ATP- dependent RNA helicase; Belongs to the DEAD box helicase family. | PFAM: NUDIX hydrolase; KEGG: fjo:Fjoh_2605 NUDIX hydrolase. | 0.619 |
| Coch_0467 | Coch_1947 | Coch_0467 | Coch_1947 | PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: gfo:GFO_1099 DeaD-like DEAD box family ATP- dependent RNA helicase; Belongs to the DEAD box helicase family. | PFAM: helicase domain protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicases; KEGG: pmo:Pmob_1535 helicase domain-containing protein. | 0.452 |
| Coch_0467 | nnrD | Coch_0467 | Coch_1065 | PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: gfo:GFO_1099 DeaD-like DEAD box family ATP- dependent RNA helicase; Belongs to the DEAD box helicase family. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.729 |
| Coch_1285 | Coch_0220 | Coch_1285 | Coch_0220 | Alpha-glucan phosphorylase; KEGG: sat:SYN_00879 glycogen synthase/glycogen phosphorylase; TIGRFAM: alpha-glucan phosphorylase; PFAM: glycogen synthase; glycosyl transferase family 35. | Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid. | 0.446 |
| Coch_1285 | Coch_1947 | Coch_1285 | Coch_1947 | Alpha-glucan phosphorylase; KEGG: sat:SYN_00879 glycogen synthase/glycogen phosphorylase; TIGRFAM: alpha-glucan phosphorylase; PFAM: glycogen synthase; glycosyl transferase family 35. | PFAM: helicase domain protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicases; KEGG: pmo:Pmob_1535 helicase domain-containing protein. | 0.555 |
| Coch_1285 | Coch_2050 | Coch_1285 | Coch_2050 | Alpha-glucan phosphorylase; KEGG: sat:SYN_00879 glycogen synthase/glycogen phosphorylase; TIGRFAM: alpha-glucan phosphorylase; PFAM: glycogen synthase; glycosyl transferase family 35. | Nicotinamidase; PFAM: isochorismatase hydrolase; KEGG: cbc:CbuK_0806 nicotinamidase. | 0.417 |
| Coch_1285 | nnrD | Coch_1285 | Coch_1065 | Alpha-glucan phosphorylase; KEGG: sat:SYN_00879 glycogen synthase/glycogen phosphorylase; TIGRFAM: alpha-glucan phosphorylase; PFAM: glycogen synthase; glycosyl transferase family 35. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.759 |
| Coch_1562 | Coch_0220 | Coch_1562 | Coch_0220 | Histidine kinase; PFAM: response regulator receiver; Two component regulator three Y domain protein; Two component regulator propeller; ATP-binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bfr:BF4234 two-component system sensor histidine kinase/response regulator hybrid. | Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid. | 0.995 |
| Coch_1562 | Coch_1947 | Coch_1562 | Coch_1947 | Histidine kinase; PFAM: response regulator receiver; Two component regulator three Y domain protein; Two component regulator propeller; ATP-binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bfr:BF4234 two-component system sensor histidine kinase/response regulator hybrid. | PFAM: helicase domain protein; type III restriction protein res subunit; SMART: helicase domain protein; DEAD-like helicases; KEGG: pmo:Pmob_1535 helicase domain-containing protein. | 0.401 |
| Coch_1562 | glmS | Coch_1562 | Coch_1372 | Histidine kinase; PFAM: response regulator receiver; Two component regulator three Y domain protein; Two component regulator propeller; ATP-binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bfr:BF4234 two-component system sensor histidine kinase/response regulator hybrid. | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.406 |
| Coch_1562 | groL | Coch_1562 | Coch_0317 | Histidine kinase; PFAM: response regulator receiver; Two component regulator three Y domain protein; Two component regulator propeller; ATP-binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bfr:BF4234 two-component system sensor histidine kinase/response regulator hybrid. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.513 |
| Coch_1562 | nnrD | Coch_1562 | Coch_1065 | Histidine kinase; PFAM: response regulator receiver; Two component regulator three Y domain protein; Two component regulator propeller; ATP-binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bfr:BF4234 two-component system sensor histidine kinase/response regulator hybrid. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.633 |
| Coch_1604 | nnrD | Coch_1604 | Coch_1065 | PFAM: protein of unknown function UPF0079; KEGG: fps:FP1067 hypothetical protein. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.690 |
| Coch_1651 | Coch_0467 | Coch_1651 | Coch_0467 | PFAM: NUDIX hydrolase; KEGG: fjo:Fjoh_2605 NUDIX hydrolase. | PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: gfo:GFO_1099 DeaD-like DEAD box family ATP- dependent RNA helicase; Belongs to the DEAD box helicase family. | 0.619 |